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The use of DILAUDID INJECTION just isn't suggested for individuals taking MAOIs or inside of 14 times of stopping these types of cure.
Check infants exposed to DILAUDID INJECTION via breast milk for excess sedation and respiratory melancholy. Withdrawal symptoms can take place in breastfed infants when maternal administration of hydromorphone is stopped, or when breast-feeding is stopped.
Observational reports have demonstrated that concomitant utilization of opioid analgesics and benzodiazepines raises the danger of drug-linked mortality in comparison with usage of opioid analgesics alone.
You shouldn’t acquire hydromorphone or morphine within fourteen times of getting a monoamine oxidase inhibitor (MAOI).
Hydromorphone wasn't mutagenic while in the in vitro bacterial reverse mutation assay (Ames assay). Hydromorphone wasn't clastogenic in possibly the in vitro human lymphocyte chromosome aberration assay or perhaps the in vivo mouse micronucleus assay.
Parenteral drug abuse is usually connected to transmission of infectious disorders including hepatitis and HIV.
Opioid analgesics, such as DILAUDID INJECTION, can extend labor through actions which quickly decrease the power, length, and frequency of uterine contractions. Nevertheless, this outcome is not really consistent and should be offset by an increased amount of cervical dilation, which has a tendency to shorten labor.
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Viagra® and generic Viagra® may influence the best way other medicines function, as well as other medicines may possibly have an impact on just how Viagra® and generic Viagra® performs, triggering Unwanted effects.
The pharmacokinetics of hydromorphone in individuals with serious hepatic check here impairment hasn't been analyzed. A further increase in Cmax and AUC of hydromorphone In this particular team is anticipated and should be taken into consideration when choosing a starting off dose [see Use In Specific Populations].
Reserve concomitant prescribing of DILAUDID Injection and benzodiazepines or other CNS depressants for use in patients for whom option procedure selections are inadequate.
Get hold of area point out Experienced licensing board or state-managed substances authority for info on how to forestall and detect abuse or diversion of the item.